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Agenta's
platform technology, patented last year, has enourmous potential for
discovery of new drugs for healing, and for tissue regeneration.
We have discovered a way to create hundreds of thousands of potentially
useful modifications to what other scientists have found to be critical
molecules in the natural growth and healing processes.
This means improvements in how well, and how fast, broken bones or
implants heal. This means improvements in spine and vertebral
disc treatments , possibly in a way that could be done without
surgery. This also means improvements in skin healing after
terrible burns, and healing of sores that won’t heal in diabetics or in
the elderly, or skin that is damaged from sun or age.
The critical molecule, and the core of Agenta’s technology, is the
proteoglycan (proteo-glycan). Proteoglycans consist of two parts;
the protein core, and long, sophisticated, glycan chains; hence the
name proteoglycan.
This class of molecules can promote healing through a variety of known
mechanisms; as required carriers and activators for important growth
factors in healing; providing structure; increasing blood supply; and
increasing tissue hydration. Accordingly, these therapeutics can
be applied to bone, cartilage, discs in the spine, and to skin, or
serve as coatings for vascular stents and implants.
We have engineered small, soluble, proprietary, drug-like
proteoglycans, and these display enhanced properties for healing and
for tissue regeneration. We also are working on proprietary drugs
that allow your own body to create a customized proteoglycan for that
same effect in wound healing and tissue regeneration. These
should provide the the most effective glycan for the job, while
circumventing the complex biological process of proteoglycan synthesis,
and keeping drug manufacturing costs lower.
Agenta is currently targeting bone healing in the mouth, and the
ability to grow new bone in the jaw and around teeth, something that
almost everyone needs as they get older. Our pre-clinical bone
data is positive, and we are also seeing early animal data that
supports skin healing.
Agenta Biotechnologies, Inc. is a team of experienced scientists,
management leaders, directors, and associates developing new drugs for
healing and regeneration. It is Agenta Biotechnologies’ mission
to be the world leader in manipulating proteoglycans for therapeutic
use.
Agenta Biotechnologies, Inc. is a privately held discovery-based
biopharmaceutical company headquartered in Birmingham, Alabama.
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